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Although the mechanistic explanation for this observation is still under investigation, recent evidence points to the possibility of non-genetic sperm mediated effects on preimplantation embryo development (Guo et al., 2017

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Numerous studies have reported that inflammation may directly and indirectly affect lung endothelia and pulmonary hemodynamics by activating inflammatory cells, such as neutrophils, macrophages, and lymphocytes, and proinflammatory mediators [13]