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(2026) Key Takeaways Standard subcutaneous dose : 5-10 mg daily for 10-20 days, administered as 1 mL injection using a 29-31 gauge insulin syringe [1] Typical cycle protocol : 10-day treatment cycles repeated every 3-6 months, based on transgenic mouse studies showing 13.5% lifespan extension [2] Half-life : Approximately 6-8 hours requiring once-daily administration for optimal telomerase activation [3] Bioavailability : Subcutaneous injection provides 85-90% bioavailability compared to 15-20% for oral administration [4] Regulatory status : Research peptide only - not FDA-approved for therapeutic use in humans Medical supervision required : Dosing protocols should be overseen by qualified healthcare providers familiar with peptide therapy Molecular weight : 390.35 Da tetrapeptide (Ala-Glu-Asp-Gly) requiring refrigerated storage at 36-46°F (2-8°C) [1] Epithalon represents a synthetic version of epithalamin, a pineal gland peptide that activates telomerase enzyme activity in human somatic cells

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[DOI] [PubMed] [Google Scholar] 70.Sourial S., Tempest N., Hapangama D.K