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Cav-1 is crucial in maintaining vascular health but a paradoxical role of Cav-1 in cardiovascular pathophysiology has also been reported 19,38

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On the other hand, in particular considering BPC 157 intragastric application, these findings are along with the abovementioned BPC 157 supposed conceptual significance as an original cytoprotective anti-ulcer peptide resistant to human gastric juice [5,6,7,8,9,10,11,12,13,14,15,16,17,18,19], and essential part of function of brain–gut axis and gut–brain axis