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It is found in a range of foods, particularly plant-based products such as grains, legumes, citrus fruits, nuts, seeds and wholegrains

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Underpinning this crosstalk is metabolic reprogramming—such as enhanced glycolysis in macrophages and increased polyunsaturated fatty acid (PUFA) synthesis in epithelial cells—which supplies the substrates necessary for both ferroptosis and immune activation, closing a vicious cycle