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​ PRESCRIPTIVE B12 VERSUS NON PRESCRIPTIVE B12 PRESCRIPTION B12 Hydroxocobalamin — NICE-recommended form used by the NHS ​ Prescribed by a GMC or NMC-registered medical practitioner ​ Medical consultation required — your safety is assessed first ​ Same clinical standard as your GP Longer-lasting and more stable in the body ​ No cyanide content ​ Administered by a qualified medical professional using correct technique ​ Monitored and reviewed — protocol adjusted to your individual needs ​ Private blood testing available to confirm deficiency and track response ​ Legal, compliant and fully documented prescription NON-PRESCRIPTION B12 Often cyanocobalamin — cheaper synthetic form not recommended by NICE ​ Not prescribed — no prescriber involved ​ No medical consultation or safety assessment required ​ Not the same standard as your GP ​ Shorter-acting and less stable ​ Contains a small amount of cyanide the body must detoxify ​ Administered by non-medical staff with no clinical oversight ​ No monitoring, no review, no adjusted protocol ​ No blood testing — deficiency not confirmed ​ No legal prescription — grey area of compliance VITAMIN B12 FAQS Vitamin B12 Injection FAQs What is the difference between hydroxocobalamin and cyanocobalamin