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doi: 10.3389/fimmu.2026.1758379 Received 01 December 2025 Revised 05 March 2026 Accepted 05 March 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Varun Sasidharan Nair, Italian Institute of Technology (IIT), Italy Reviewed by Mahmoud Abdelrahman Alkabbani, Egyptian Russian University, Egypt Lingjie Meng, Zunyi Medical University, China Updates Copyright © 2026 Sivalingam
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One of the best-known examples of a peroxidase-based redox relay is the yeast glutathione peroxidase-like enzyme Orp1 (Gpx3), which transfers oxidative equivalents to the yeast oxidative stress transcription factor Yap1 via the formation of an intermolecular disulfide bond [108–110]