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Scientific Communications: intracranial hemorrhage 02.00 - INTRACRANIAL HEMORRHAGE - 02.01 - INTRACEREBRAL HAEMORRHAGE O - ESOC25-1919 THE EFFECT OF EARLY MINIMALLY INVASIVE SURGICAL HAEMATOMA EVACUATION ON PERIHAEMATOMAL OEDEMA FORMATION Maaike Cliteur 1 , Lotte Sondag 2 , Wilmar Jolink 3 , William Peter Vandertop 4 , Jeroen Boogaarts 5 , Marieke Wermer 6 , Ruben Dammers 7 , Floris Schreuder 1 , Karin Klijn 1 1 Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, Netherlands, 2 Department of Neurology, Jeroen Bosch Hospital, 's Hertogenbosch, Netherlands, 3 Department of Neurology, Isala Hospital, Zwolle, Netherlands, 4 Amsterdam UMC, Neurosurgery, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands, 5 Department of Neurosurgery, Radboud University Medical Centre, Nijmegen, Netherlands, 6 Department of Neurology, University Medical Center Groningen (UMCG), Groningen, Netherlands, 7 Department of Neurosurgery, Erasmus Medical Centre, Erasmus MC Stroke Centre, Rotterdam, Netherlands Background and Aims: In patients with intracerebral haemorrhage (ICH), perihaematomal oedema (PHO) is considered a marker of secondary injury and is independently associated with worse functional outcomes
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It is strongly associated with mechanical ventilation and extensive damage to the basement membrane, where inadequate or delayed re-epithelialization can lead to the development of changes such as interstitial fibrosis
