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Thus far, paradigms to explain the desensitization pattern of β 1 -ARs are primarily based on the β 2 -AR

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Gene expression scope: Pickart and colleagues reported in transcriptomic analyses that GHK influences expression of more than 4,000 human genes when modeled in silico using the Connectivity Map database, including upregulation of antioxidant genes (SOD1, catalase pathway genes) and downregulation of inflammatory transcription factor NF-kB targets